MOTS-c

MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA-c) is a mitochondrial-derived peptide consisting of 16 amino acids, encoded within the 12S ribosomal RNA gene of the mitochondrial genome. Its discovery represented a significant advancement in mitochondrial biology research, establishing that mitochondria produce bioactive peptides capable of regulating systemic metabolic function. It is one of the most rapidly emerging research peptides available to researchers today.

Researchers have investigated MOTS-c across a broad range of in vitro and in vivo models, with published studies exploring its role in AMPK pathway activation, glucose metabolism regulation, and mitochondrial biogenesis. Of particular interest to researchers is MOTS-c’s apparent ability to translocate to the nucleus in response to metabolic stress, where it has been shown to regulate nuclear gene expression related to oxidative stress response and metabolic adaptation. Published research has also examined its interactions with insulin sensitivity pathways, skeletal muscle metabolism, and age-related metabolic decline models, with researchers noting significant attenuation of metabolic dysfunction in preclinical aging models.

MOTS-c is consistently selected by researchers studying mitochondrial biology, metabolic pathway regulation, and longevity-related research models, and represents one of the most promising emerging compounds in the mitochondrial peptide research space.

MOTS-c Supply by Chains Peptide Malaysia

Chains Peptide Malaysia provides MOTS-c to qualified researchers throughout Malaysia from our local inventory. We are 100% owned, operated, and shipped directly from Malaysia. When you purchase MOTS-c from Chains Peptide Malaysia, you will receive a physical Certificate of Analysis (COA) with each order. To prevent online fraud and unauthorized use, COAs are not provided digitally and are not intended for marketing purposes. All orders ship the same day from Malaysia, accompanied by full chain of custody documentation.

For research use only. Not for human or veterinary use. For use by qualified researchers in appropriate laboratory settings only.

CAS Number: 1627580-64-6

Molecular Weight (g/moL): 2174.6

Molecular Formula: C101H152N28O22S2

Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

Format: White Lyophilized Powder

Database Link