TB-500 is a synthetic analogue of Thymosin Beta-4, a naturally occurring peptide found in virtually all human and animal cells. It has been the subject of significant preclinical research, making it one of the most widely studied peptides available to Canadian researchers today.
Researchers have investigated TB-500 across a broad range of in vitro and in vivo models, with published studies exploring its role in actin polymerisation regulation, specifically its binding to G-actin via its highly conserved LKKTET sequence. This mechanism has been of particular interest to researchers studying cell migration, tissue remodelling, and wound healing response pathways. Additional preclinical research has examined TB-500’s interactions with vascular endothelial growth factor (VEGF) signalling, metalloproteinase regulation, and anti-inflammatory cytokine modulation in models relating to musculoskeletal and connective tissue repair.
TB-500 is frequently paired with BPC-157 (Pentadecapeptide) in multi-compound research protocols due to their complementary mechanistic profiles — BPC-157 operating primarily through nitric oxide and growth hormone receptor pathways, while TB-500 acts predominantly through actin regulation and cellular migration mechanisms.
TB-500 Supply by Chains Peptide Malaysia
Chains Peptide Malaysia provides TB-500 to qualified researchers throughout Malaysia from our local inventory. We are 100% owned, operated, and shipped directly from Malaysia. When you purchase TB-500 from Chains Peptide Malaysia, you will receive a physical Certificate of Analysis (COA) with each order. To prevent online fraud and unauthorized use, COAs are not provided digitally and are not intended for marketing purposes. All orders ship the same day from Malaysia, accompanied by full chain of custody documentation.
For research use only. Not for human or veterinary use. For use by qualified researchers in appropriate laboratory settings only.
CAS Number: 77591-33-4
Molecular Weight (g/moL): 4963.44
Molecular Formula: C212H350N56O78S
Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Format: White Lyophilized Powder









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